No. 22 Biggest Rent Hike: Oxnard-Thousand Oaks-Ventura, Calif.

Annual increase: 5.8%
Average monthly rent: $1,493
Vacancy rate: 4.6% (5.4% in 2009)
Average concession: -2%

Major employers in this part of Southern California include biotech company Amgen and the U.S. Navy, according to the state's Employment Development Dept. Unemployment rose to an annual average of about 10.9 percent last year, according to estimates using BLS preliminary data, compared with about 10 percent in 2009. As vacancies fell, some renters in the Simi Valley and Moorpark areas paid 8.6 percent more in 2010 than a year earlier, according to AXIOMetrics data. The firm expects rents in the metro area to increase an additional 5.6 percent in 2011.

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