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Trained as an architect in London, Sinclair, 36, co-founded a nonprofit, social, and humanitarian-focused organization called Architecture for Humanity (AfH) in 1999. Headquartered in San Francisco, AfH now has 53 chapters of 4,650 volunteers working on projects in 13 locations around the world. Working to promote the power of design as "the ultimate renewable resource," Sinclair & Co. most recently leaped into action to help in Haiti, mobilizing forces to provide immediate shelter as well as plan longer-term reconstruction after the country's crushing earthquake.